TY - JOUR
T1 - Zygote intrafallopian transfer among patients with repeated implantation failure
AU - Weissman, Ariel
AU - Horowitz, Eran
AU - Ravhon, Amir
AU - Nahum, Hana
AU - Golan, Abraham
AU - Levran, David
PY - 2013/1
Y1 - 2013/1
N2 - Objective: To summarize the experience of a single center with laparoscopic zygote intrafallopian transfer (ZIFT) performed exclusively among patients with high-order repeated implantation failure (RIF) following in vitro fertilization-embryo transfer (IVF-ET). Methods: A retrospective cohort study was performed at the Edith Wolfson Medical Center, a tertiary referral university hospital located in Holon, Israel. A group of 176 patients with 8.15 ± 3.9 previously failed IVF-ET cycles underwent 280 ZIFT procedures between 1995 and 2010. The main outcome measure was the live birth rate per patient treated. Results: In all, there were 274 fresh and 6 frozen ZIFT cycles recorded in the study cohort, resulting in 96 clinical pregnancies per attempt (34.3%) and 72 live births (25.7%). The live birth rate per patient was 39.8%. Conclusion: The use of ZIFT remains a powerful tool in the clinical management of selected patients with high-order RIF. This procedure should be kept in mind when all other measures fail among patients with at least 1 unobstructed fallopian tube.
AB - Objective: To summarize the experience of a single center with laparoscopic zygote intrafallopian transfer (ZIFT) performed exclusively among patients with high-order repeated implantation failure (RIF) following in vitro fertilization-embryo transfer (IVF-ET). Methods: A retrospective cohort study was performed at the Edith Wolfson Medical Center, a tertiary referral university hospital located in Holon, Israel. A group of 176 patients with 8.15 ± 3.9 previously failed IVF-ET cycles underwent 280 ZIFT procedures between 1995 and 2010. The main outcome measure was the live birth rate per patient treated. Results: In all, there were 274 fresh and 6 frozen ZIFT cycles recorded in the study cohort, resulting in 96 clinical pregnancies per attempt (34.3%) and 72 live births (25.7%). The live birth rate per patient was 39.8%. Conclusion: The use of ZIFT remains a powerful tool in the clinical management of selected patients with high-order RIF. This procedure should be kept in mind when all other measures fail among patients with at least 1 unobstructed fallopian tube.
KW - In vitro fertilization-embryo transfer
KW - Repeated implantation failure
KW - Zygote intrafallopian transfer
UR - http://www.scopus.com/inward/record.url?scp=84871720574&partnerID=8YFLogxK
U2 - 10.1016/j.ijgo.2012.07.018
DO - 10.1016/j.ijgo.2012.07.018
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AN - SCOPUS:84871720574
VL - 120
SP - 70
EP - 73
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
SN - 0020-7292
IS - 1
ER -