In 19 children affected with acute leukemia the serum immunoglobulin level was examined. An Ig deficiency treated with a single administration of IgA or IgM concentrate could be detected in 16 of these children. The impact of this single Ig substitution on the serum immunoglobulin level and on B-lymphocytes in the peripheral blood was three times examined after this substitution. A significant increase of the corresponding Ig class in the serum and a significant decrease of B-lymphocytes in the peripheral blood could be observed.
|Translated title of the contribution||Qualitative and quantitative behavior of B lymphocytes and serum immunoglobulins in children with acute leukemia after a single immunoglobulin concentrate substitution|
|Number of pages||8|
|State||Published - 1981|