Xeniafaraunol A and B, and faraunatin; three new cytotoxic diterpenes from the soft coral xenia faraunensis

Y. Kashman; M. Saltoun; A. Rudi; Y. Benayahu

doi:10.1016/S0040-4039(00)78516-9

Xeniafaraunol A and B, and faraunatin; three new cytotoxic diterpenes from the soft coral xenia faraunensis

Y. Kashman, M. Saltoun, A. Rudi, Y. Benayahu

Research output: Contribution to journal › Article › peer-review

Abstract

The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spectral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton and faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Compounds 1-3 are cytotoxic against P388 cells.

Original language	English
Pages (from-to)	8855-8858
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	47
DOIs	https://doi.org/10.1016/S0040-4039(00)78516-9
State	Published - 21 Nov 1994

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title = "Xeniafaraunol A and B, and faraunatin; three new cytotoxic diterpenes from the soft coral xenia faraunensis",

abstract = "The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spectral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton and faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Compounds 1-3 are cytotoxic against P388 cells.",

author = "Y. Kashman and M. Saltoun and A. Rudi and Y. Benayahu",

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AU - Rudi, A.

AU - Benayahu, Y.

PY - 1994/11/21

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N2 - The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spectral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton and faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Compounds 1-3 are cytotoxic against P388 cells.

AB - The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spectral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton and faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Compounds 1-3 are cytotoxic against P388 cells.

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Xeniafaraunol A and B, and faraunatin; three new cytotoxic diterpenes from the soft coral xenia faraunensis

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