@article{c6e34d85f7fc4031b84fc1e93e9ed829,
title = "Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans",
abstract = "Uncovering the neural mechanisms underlying human natural ambulatory behavior is a major challenge for neuroscience. Current commercially available implantable devices that allow for recording and stimulation of deep brain activity in humans can provide invaluable intrinsic brain signals but are not inherently designed for research and thus lack flexible control and integration with wearable sensors. We developed a mobile deep brain recording and stimulation (Mo-DBRS) platform that enables wireless and programmable intracranial electroencephalographic recording and electrical stimulation integrated and synchronized with virtual reality/augmented reality (VR/AR) and wearables capable of external measurements (e.g., motion capture, heart rate, skin conductance, respiration, eye tracking, and scalp EEG). When used in freely moving humans with implanted neural devices, this platform is adaptable to ecologically valid environments conducive to elucidating the neural mechanisms underlying naturalistic behaviors and to the development of viable therapies for neurologic and psychiatric disorders.",
keywords = "augmented reality, eye tracking, human, intracranial EEG, intracranial electrical stimulation, mobile EEG, neuroimaging methods, virtual reality, wearables",
author = "Uros Topalovic and Aghajan, {Zahra M.} and Diane Villaroman and Sonja Hiller and Leonardo Christov-Moore and Wishard, {Tyler J.} and Matthias Stangl and Hasulak, {Nicholas R.} and Inman, {Cory S.} and Fields, {Tony A.} and Rao, {Vikram R.} and Dawn Eliashiv and Itzhak Fried and Nanthia Suthana",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = oct,
day = "28",
doi = "10.1016/j.neuron.2020.08.021",
language = "אנגלית",
volume = "108",
pages = "322--334.e9",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "2",
}