Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital

I. Shalit; S. A. Berger; A. Gorea; H. Frimerman

doi:10.1128/AAC.33.4.593

Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital

I. Shalit
, S. A. Berger
, A. Gorea
, H. Frimerman

Tel-Aviv Medial Center

Research output: Contribution to journal › Article › peer-review

131 Scopus citations

Abstract

Ofloxacin and ciprofloxacin resistance (MIC, >4 μg/ml) was encountered in 45 of 50 clinical isolates of methicillin-resistant Staphylococcus aureus. None of 20 methicillin-susceptible strains was resistant to the quinolones (P < 10^-6). Quinolone-susceptible and -resistant isolates did not differ with respect to culture source or bacteriophage type. The future usefulness of quinolones for S. aureus infection may be limited.

Original language	English
Pages (from-to)	593-594
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	33
Issue number	4
DOIs	https://doi.org/10.1128/AAC.33.4.593
State	Published - 1989
Externally published	Yes

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10.1128/AAC.33.4.593

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abstract = "Ofloxacin and ciprofloxacin resistance (MIC, >4 μg/ml) was encountered in 45 of 50 clinical isolates of methicillin-resistant Staphylococcus aureus. None of 20 methicillin-susceptible strains was resistant to the quinolones (P < 10-6). Quinolone-susceptible and -resistant isolates did not differ with respect to culture source or bacteriophage type. The future usefulness of quinolones for S. aureus infection may be limited.",

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AB - Ofloxacin and ciprofloxacin resistance (MIC, >4 μg/ml) was encountered in 45 of 50 clinical isolates of methicillin-resistant Staphylococcus aureus. None of 20 methicillin-susceptible strains was resistant to the quinolones (P < 10-6). Quinolone-susceptible and -resistant isolates did not differ with respect to culture source or bacteriophage type. The future usefulness of quinolones for S. aureus infection may be limited.

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Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital

Abstract

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