Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital

I. Shalit, S. A. Berger, A. Gorea, H. Frimerman

Research output: Contribution to journalArticlepeer-review

131 Scopus citations

Abstract

Ofloxacin and ciprofloxacin resistance (MIC, >4 μg/ml) was encountered in 45 of 50 clinical isolates of methicillin-resistant Staphylococcus aureus. None of 20 methicillin-susceptible strains was resistant to the quinolones (P < 10-6). Quinolone-susceptible and -resistant isolates did not differ with respect to culture source or bacteriophage type. The future usefulness of quinolones for S. aureus infection may be limited.

Original languageEnglish
Pages (from-to)593-594
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume33
Issue number4
DOIs
StatePublished - 1989
Externally publishedYes

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