Widely disseminated cutaneous candidosis in adults

I. Alteras*, E. J. Feuerman, M. David, Beatrice Shohat, Ella Livni

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Of 9 adults, 5 males, 4 females, with wide dissemination of Candida albicans skin lesions, the eruption started in the groin, from which it spread to other areas in most cases. In 5 cases the disseminated lesions were papulo-pustular; the rest were erythematous-squamous. Hyphae and yeast cells of C. albicans were found on direct microscopy. Diabetes was present in 5 patients, lymphoma in 1, and bullous pemphigoid in another. Onychia and paronychia were found in 7 patients, intertriginous lesions of the fingers in 4 and oral thrush in 2. Intradermal skin tests were negative. The percentage and absolute numbers of T-lymphocytes were normal in 6 of 7 patients, whereas their functional activity was impaired in 4 of 6 patients, as evidenced by the negative Graft-versus host reaction. The role of concurrent disease in the pathogenesis of the candidosis is discussed.

Original languageEnglish
Pages (from-to)383-388
Number of pages6
JournalMedical Mycology
Volume17
Issue number4
DOIs
StatePublished - 1979

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