TY - JOUR
T1 - Wide-range C-reactive protein efficacy in acute ischemic stroke patients
AU - Shenhar-Tsarfaty, S.
AU - Ben Assayag, E.
AU - Bova, I.
AU - Vered, Y.
AU - Berliner, S.
AU - Rogowski, O.
AU - Shapira, I.
AU - Bornstein, N. M.
PY - 2006/7
Y1 - 2006/7
N2 - Objective - To compare the recently introduced wide-range C-reactive protein (wr-CRP) with the widely used high-sensitivity Behring Dade method (hs-CRP) in acute stroke/transient ischemic attack (TIA) patients. Materials and methods - A total of 119 consecutive patients admitted to a tertiary medical center with acute ischemic stroke/TIA were included in the study. Venous blood was obtained for both assays during the first 24 h, 3-5 days, as well as 3-6 months thereafter. Results - A highly significant correlation (r = 0.994, P < 0.0001) was found between the two methods even when analyzed at three different time points. In addition, a similar correlation was noted between these two assays and other commonly used biomarkers, including white blood cell count, Westergren's sedimentation rate and quantitative fibrinogen. Conclusion - Real-time, on-line and low-cost wr-CRP assay is a reasonable alternative to the Behring Dade hs-CRP method in acute stroke/TIA patients.
AB - Objective - To compare the recently introduced wide-range C-reactive protein (wr-CRP) with the widely used high-sensitivity Behring Dade method (hs-CRP) in acute stroke/transient ischemic attack (TIA) patients. Materials and methods - A total of 119 consecutive patients admitted to a tertiary medical center with acute ischemic stroke/TIA were included in the study. Venous blood was obtained for both assays during the first 24 h, 3-5 days, as well as 3-6 months thereafter. Results - A highly significant correlation (r = 0.994, P < 0.0001) was found between the two methods even when analyzed at three different time points. In addition, a similar correlation was noted between these two assays and other commonly used biomarkers, including white blood cell count, Westergren's sedimentation rate and quantitative fibrinogen. Conclusion - Real-time, on-line and low-cost wr-CRP assay is a reasonable alternative to the Behring Dade hs-CRP method in acute stroke/TIA patients.
KW - Stroke
KW - Transient ischemic attack
KW - Wide-range C-reactive protein
UR - http://www.scopus.com/inward/record.url?scp=33745038976&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0404.2005.00572.x
DO - 10.1111/j.1600-0404.2005.00572.x
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C2 - 16774624
AN - SCOPUS:33745038976
SN - 0001-6314
VL - 114
SP - 29
EP - 32
JO - Acta Neurologica Scandinavica
JF - Acta Neurologica Scandinavica
IS - 1
ER -