When uncommon and common coalesce: adult onset Still’s disease associated with breast augmentation as part of autoimmune syndrome induced by adjuvants (ASIA)

A. Dagan, M. Kogan, Y. Shoenfeld, G. Segal

Research output: Contribution to journalReview articlepeer-review

Abstract

Adult onset Still’s disease (AOSD) is an uncommon, multisystemic, auto-inflammatory disorder, while breast augmentation is a very common cosmetic procedure. We describe a case in which these two coalesce, AOSD, manifested with pleuritis and pericarditis, developed after breast mammoplasty. The pathogenetic, missing link, behind the development of AOSD following mammoplasty, is thought to be the autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA). We reviewed other cases of AOSD associated with breast mammoplasty published to date and the literature regarding AOSD and ASIA syndrome. The review is followed by a short debate of whether silicone implants should be explanted in similar, future cases.

Original languageEnglish
Pages (from-to)1643-1648
Number of pages6
JournalClinical Rheumatology
Volume35
Issue number6
DOIs
StatePublished - 1 Jun 2016

Keywords

  • ASIA syndrome
  • Adjuvants
  • Autoimmunity
  • Breast mammoplasty
  • Silicone implants
  • Still’s disease

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