When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity

Penelope Lowe, Amir Krivoy*, Lilla Porffy, Erna Henriksdottir, Whiskey Eromona, Sukhwinder S. Shergill

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Treatment-resistant schizophrenia is a serious clinical problem. We adopt a systems-level approach positing a greater role for cognitive control mechanisms in the development of psychotic symptoms and illustrate the clinical application of this via a case report of treatment-resistant patients treated successfully with adjunct pro-cognitive serotonergic medication.

Original languageEnglish
Pages (from-to)63-70
Number of pages8
JournalTherapeutic Advances in Psychopharmacology
Volume8
Issue number1
DOIs
StatePublished - 1 Jan 2018
Externally publishedYes

Keywords

  • cognition
  • novel treatment
  • refractory schizophrenia

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