Wettability engineering and bioactivation of hydroxyapatite nanoceramics

G. Rosenman, D. Aronov

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The major trends in biotechnology and tissue engineering are development of materials with controlled surface substrates. One of the critical factors influencing adhesion of biocells is wettability properties of the biomimetic materials. Hydrophilicity/hydrophobicity of any solid state surface depends on interfacial physical properties which can be varied by topographic nanostructuring, surface chemical modification and external electric field. We report about new method enabling reversible switching or gradual transition of wettability properties of materials by surface potential modulation. The use of low energy electron irradiation allows achieving tunable wettability of the hydroxyapatite in a wide range of contact angles from 10° to 100° with accuracy of ±3°. Tailoring the gradually varied wettability state in the hydroxyapatite nanoceramics enabled the differential binding of various biological cells as well adhesion of various sorts of bacteria demonstrating their selective immobilization.

Original languageEnglish
Title of host publication2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Pages91-94
Number of pages4
StatePublished - 2006
Event2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings - Boston, MA, United States
Duration: 7 May 200611 May 2006

Publication series

Name2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Volume2

Conference

Conference2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Country/TerritoryUnited States
CityBoston, MA
Period7/05/0611/05/06

Keywords

  • Bioactivation
  • Biocells adhesion
  • Hydroxyapatite nanoceramics and implant coating
  • Low energy electron irradiation
  • Wettability modification
  • Wettability patterning

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