TY - JOUR
T1 - Werner's syndrome (adult progeria)
T2 - An affected mother and son presenting with resistant psychosis
AU - Barak, Y.
AU - Sirota, P.
AU - Kimhi, R.
AU - Slor, H.
PY - 2001
Y1 - 2001
N2 - Age-related psychotic conditions may be studied by focusing on the unique group of progeroid syndromes. This report will focus on Werner's syndrome, one of the better defined and studied progeroid syndromes. We applied clinical and histophysiological evaluations to two patients, a mother and son, suffering from Werner's syndrome. Both patients presented with resistant psychosis and evidence of impaired cellular repair mechanisms. Psychiatric morbidity in Werner's syndrome is rarely reported. This syndrome can serve as a possible model for aging-associated development of psychosis.
AB - Age-related psychotic conditions may be studied by focusing on the unique group of progeroid syndromes. This report will focus on Werner's syndrome, one of the better defined and studied progeroid syndromes. We applied clinical and histophysiological evaluations to two patients, a mother and son, suffering from Werner's syndrome. Both patients presented with resistant psychosis and evidence of impaired cellular repair mechanisms. Psychiatric morbidity in Werner's syndrome is rarely reported. This syndrome can serve as a possible model for aging-associated development of psychosis.
UR - http://www.scopus.com/inward/record.url?scp=0035177905&partnerID=8YFLogxK
U2 - 10.1053/comp.2001.27895
DO - 10.1053/comp.2001.27895
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AN - SCOPUS:0035177905
SN - 0010-440X
VL - 42
SP - 508
EP - 510
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 6
ER -