Werner's syndrome (adult progeria): An affected mother and son presenting with resistant psychosis

Y. Barak, P. Sirota, R. Kimhi, H. Slor

Research output: Contribution to journalArticlepeer-review

Abstract

Age-related psychotic conditions may be studied by focusing on the unique group of progeroid syndromes. This report will focus on Werner's syndrome, one of the better defined and studied progeroid syndromes. We applied clinical and histophysiological evaluations to two patients, a mother and son, suffering from Werner's syndrome. Both patients presented with resistant psychosis and evidence of impaired cellular repair mechanisms. Psychiatric morbidity in Werner's syndrome is rarely reported. This syndrome can serve as a possible model for aging-associated development of psychosis.

Original languageEnglish
Pages (from-to)508-510
Number of pages3
JournalComprehensive Psychiatry
Volume42
Issue number6
DOIs
StatePublished - 2001

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