TY - JOUR
T1 - Weight loss and bronchopulmonary dysplasia in very low birth weight infants
AU - Maayan-Metzger, Ayala
AU - Mazkereth, Ram
AU - Kuint, Jacob
PY - 2008/12
Y1 - 2008/12
N2 - □ Our objective was to evaluate the extent of weight loss in very low birth weight (VLBW) preterm infants and to discover how weight loss and other variables correlate with bronchopulmonary dysplasia (BPD). We conducted an observational study of 387 VLBW preterms, gestational age (GA) < 33 weeks, in a single institution over a period of 5 years. The mean weight loss of AGA infants was significantly greater than that of SGA infants. In AGA infants, GA, z-score, weight loss, and male sex were found to correlate with BPD. After adjustments were made for GA and birth weight, each 10% loss of body weight increasesd the risk for developing BPD by a factor of 2.7. We concluded that excessive weight loss does not prevent BPD in VLBW preterms and presumably should be prevented. Controlled fluid restriction resulting in milder weight loss is probably the right choice.
AB - □ Our objective was to evaluate the extent of weight loss in very low birth weight (VLBW) preterm infants and to discover how weight loss and other variables correlate with bronchopulmonary dysplasia (BPD). We conducted an observational study of 387 VLBW preterms, gestational age (GA) < 33 weeks, in a single institution over a period of 5 years. The mean weight loss of AGA infants was significantly greater than that of SGA infants. In AGA infants, GA, z-score, weight loss, and male sex were found to correlate with BPD. After adjustments were made for GA and birth weight, each 10% loss of body weight increasesd the risk for developing BPD by a factor of 2.7. We concluded that excessive weight loss does not prevent BPD in VLBW preterms and presumably should be prevented. Controlled fluid restriction resulting in milder weight loss is probably the right choice.
KW - BPD
KW - Preterm
KW - VLBW
KW - Weight loss
UR - http://www.scopus.com/inward/record.url?scp=52149102035&partnerID=8YFLogxK
U2 - 10.1080/15513810802319533
DO - 10.1080/15513810802319533
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AN - SCOPUS:52149102035
SN - 1551-3815
VL - 27
SP - 215
EP - 222
JO - Fetal and Pediatric Pathology
JF - Fetal and Pediatric Pathology
IS - 4-5
ER -