Waldenström's macroglobulinemia associated with AA amyloidosis

J. Gardyn; A. Schwartz; R. Gal; U. Lewinski; D. Kristt; A. M. Cohen

doi:10.1007/BF02982553

Waldenström's macroglobulinemia associated with AA amyloidosis

J. Gardyn, A. Schwartz, R. Gal, U. Lewinski, D. Kristt, A. M. Cohen^*

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

It is widely accepted that amyloidosis in Waldenström's macroglobulinemia (WM) is exclusively due to amyloid light-chain deposition. However, only a small number of previous reports have actually characterized the type of amyloid in WM. We now report the third patient with WM and amyloid A protein (AA) amyloidosis. This patient developed malabsorption, nephrotic syndrome, and orthostatic hypotension. AA was immunohistochemically demonstrated in the rectal biopsy. In conjunction with previous examples of AA amyloidosis, the present report raises the possibility that AA amyloidosis may also occur in WM patients.

Original language	English
Pages (from-to)	76-78
Number of pages	3
Journal	International Journal of Hematology
Volume	74
Issue number	1
DOIs	https://doi.org/10.1007/BF02982553
State	Published - 2001

Keywords

Nephrotic syndrome
Secondary amyloidosis
Waldenström's macroglobulinemia

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10.1007/BF02982553

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abstract = "It is widely accepted that amyloidosis in Waldenstr{\"o}m's macroglobulinemia (WM) is exclusively due to amyloid light-chain deposition. However, only a small number of previous reports have actually characterized the type of amyloid in WM. We now report the third patient with WM and amyloid A protein (AA) amyloidosis. This patient developed malabsorption, nephrotic syndrome, and orthostatic hypotension. AA was immunohistochemically demonstrated in the rectal biopsy. In conjunction with previous examples of AA amyloidosis, the present report raises the possibility that AA amyloidosis may also occur in WM patients.",

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AU - Kristt, D.

AU - Cohen, A. M.

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KW - Secondary amyloidosis

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Waldenström's macroglobulinemia associated with AA amyloidosis

Abstract

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