Vitiligo

Hagit Matz, Ethel Tur

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Vitiligo is an acquired depigmentary disorder of the skin that results from the selective destruction of melanocytes. The etiology of vitiligo is poorly understood. There appears to be a genetic predisposition, but additional factors are probably involved. The purpose of this article is to outline the factors that might play a role in the development of vitiligo. These include trauma such as vaccination, radiotherapy, and sun exposure, malignancies and treatment of malignancies like lymphoma or melanoma, bone marrow transplantation, interferon, interleukin, and other drugs, psychological factors, endocrine disease and cytotoxic compounds that cause contact vitiligo. We hope future research will shed more light on the subject and identify the precipitating factors, since in the majority of vitiligo cases the contributing factors are as yet unidentified.

Original languageEnglish
Title of host publicationEnvironmental Factors in Skin Diseases
EditorsEthel Tur
Pages78-102
Number of pages25
DOIs
StatePublished - 2007
Externally publishedYes

Publication series

NameCurrent Problems in Dermatology
Volume35
ISSN (Print)1421-5721

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