Vitamin B6 (Pyridoxine) - Excessive dosage in food supplements and OTC medications

N. Barak*, D. Huminer, B. Stahl

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Vitamin B6 (Pyridoxine) is sold in Israel as a supplement and is available over-the-counter (OTC) without regulation. High intake of this vitamin is found in patients with premenstrual syndrome, carpal tunnel syndrome, pregnancy associated nausea and vomiting, decreasing homocysteine levels and improving cognitive function. Mega-doses of this vitamin may result in intoxication. In this review we will outline vitamin B6 function, daily recommended intake, deficiency signs and patients in deficiency risk, and the clinical spectrum of vitamin B6 intoxication.

Original languageEnglish
Pages (from-to)887-890
Number of pages4
Issue number12
StatePublished - Dec 2004
Externally publishedYes


  • Deficiency
  • Intoxication
  • Pyridoxine
  • Supplement
  • Vitamin B6


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