Virulence patterns from septicemic Escherichia coli O78 strains

Reuven Babai, Gabriele Blum-Oehler, Baruch E. Stern, Jörg Hacker, Eliora Z. Ron*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Several septicemic Escherichia coli O78 strains, isolated from different sources, were characterized phenotypically and genotypically. Two avian isolates, one of which is known to carry the AC/I fimbriae, hybridized with the sfa determinant in colony dot-blot assay. Southern hybridizations with specific sfa probes, following pulsed-field gel electrophoresis (PFGE), showed positive hybridization to the same fragment in each of these strains. Determination of the N-terminal amino acid sequence of the AC/I major subunit gene revealed high similarity to the sequence of the SfaA-II protein. These data suggest that the adhesin gene cluster, coding for AC/I fimbriae, belongs to the S-fimbrial adhesin family.

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalFEMS Microbiology Letters
Volume149
Issue number1
DOIs
StatePublished - 1 Apr 1997

Keywords

  • AC/I fimbria
  • Escherichia coli serotype O78
  • S-Fimbria
  • Septicemia
  • Virulence factor

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