TY - JOUR
T1 - ViroidDB
T2 - A database of viroids and viroid-like circular RNAs
AU - Lee, Benjamin D.
AU - Neri, Uri
AU - Oh, Caleb J.
AU - Simmonds, Peter
AU - Koonin, Eugene V.
N1 - Publisher Copyright:
© 2022 Published by Oxford University Press on behalf of Nucleic Acids Research.
PY - 2022/1/7
Y1 - 2022/1/7
N2 - We introduce ViroidDB, a value-added database that attempts to collect all known viroid and viroid-like circular RNA sequences into a single resource. Spanning about 10 000 unique sequences, ViroidDB includes viroids, retroviroid-like elements, small circular satellite RNAs, ribozyviruses, and retrozymes. Each sequence's secondary structure, ribozyme content, and cluster membership are predicted via a custom pipeline optimized for handling circular RNAs. The data can be explored via a purpose-built user interface that features visualizations, multiple sequence alignments, and a portal for downloading bulk data. Users can browse the data by sequence type, taxon, or typo-tolerant search of metadata fields. The database is freely accessible at https://viroids.org.
AB - We introduce ViroidDB, a value-added database that attempts to collect all known viroid and viroid-like circular RNA sequences into a single resource. Spanning about 10 000 unique sequences, ViroidDB includes viroids, retroviroid-like elements, small circular satellite RNAs, ribozyviruses, and retrozymes. Each sequence's secondary structure, ribozyme content, and cluster membership are predicted via a custom pipeline optimized for handling circular RNAs. The data can be explored via a purpose-built user interface that features visualizations, multiple sequence alignments, and a portal for downloading bulk data. Users can browse the data by sequence type, taxon, or typo-tolerant search of metadata fields. The database is freely accessible at https://viroids.org.
UR - http://www.scopus.com/inward/record.url?scp=85123089031&partnerID=8YFLogxK
U2 - 10.1093/nar/gkab974
DO - 10.1093/nar/gkab974
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C2 - 34751403
AN - SCOPUS:85123089031
SN - 0305-1048
VL - 50
SP - D432-D438
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - D1
ER -