Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic?

Or Kriger*, Shiraz Gefen-Halevi, Eyal Leshem, Gillian Smollan, Natasha Belausov, Aseel Egbarye, Rawan Khashab, Miran Odeh, Adleen Saffia, Yuval Barak, Oswa Abu Hussein, Rachel Hamias, Yael Aharon, Jacqueline Alfandari, Ital Nemet, Limor Kliker, Hilda Sherbany, Michal Mandelboim, Sharon Amit

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Objective: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. Methods: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples of patients admitted to our hospital with acute respiratory infection (ARI) between March 1, 2020, and February 28, 2021. We matched 40 to 50 patients who were SARS-CoV-2 positive and SARS-CoV-2 negative per month for age and sex. Results: A total of 939 patients with multiplex PCR test results were included in the study. Respiratory pathogens where detected in only 8/476 (1.6%) patients with COVID-19 versus 87/463 (18.7%) patients with non–COVID-19 ARI patients. Diversity and rates of pathogens vastly differed from previous years but showed seasonal variance. Conclusion: Patients with SARS-CoV-2 infection presenting with ARI during the first year of the COVID-19 pandemic demonstrated paucity of respiratory co-pathogens.

Original languageEnglish
Pages (from-to)226-229
Number of pages4
JournalInternational Journal of Infectious Diseases
Volume116
DOIs
StatePublished - Mar 2022

Keywords

  • COVID-19
  • SARS-CoV-2
  • co-infections

Fingerprint

Dive into the research topics of 'Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic?'. Together they form a unique fingerprint.

Cite this