VIP1 receptors are present in breast cancer cells, VIP elevates the cAMP and stimulates nuclear oncogene expression in MCF-7 cells. VIPhybrid is a VIP receptor antagonist that inhibits breast cancer proliferation. A VIP analog has been developed for imaging breast tumors. Therefore VIP1 receptors may be utilized for the early detection and treatment of breast cancer.
|Number of pages||7|
|Journal||Annals of the New York Academy of Sciences|
|State||Published - 1998|