Vigabatrin and multifocal myoclonus in adults with partial seizures

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15 Scopus citations

Abstract

We report the appearance of multifocal myoclonus in two adult patients treated with vigabatrin as an add-on drug for complex partial seizures. The myoclonus subsided after dose reduction or discontinuation of the drug. There were no electroencephalogram correlates during the myoclonic jerks. This phenomenon may represent a apparently dose-related rare adverse drug event, similar to that seen occasionally with other anticonvulsants.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalClinical Neuropharmacology
Volume18
Issue number3
DOIs
StatePublished - 1995
Externally publishedYes

Keywords

  • Myoclonus
  • Nonepileptic myoclonus
  • Vigabatrin

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