TY - JOUR
T1 - Vertebral hemangiomas
T2 - their demographical characteristics, location along the spine and position within the vertebral body
AU - Slon, Viviane
AU - Stein, Dan
AU - Cohen, Haim
AU - Sella-Tunis, Tatiana
AU - May, Hila
AU - Hershkovitz, Israel
N1 - Publisher Copyright:
© 2015, Springer-Verlag Berlin Heidelberg.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Purpose: Vertebral hemangiomas (VHs) are the most common form of benign tumors in the spine. The aim of this research was to study the prevalence of VHs in the human population, their distribution along the spine and their location in the vertebral body. Methods: The presence of VHs was assessed in full spine CT scans of 196 adults. Demographic data were gathered from medical records. Results: VHs were present in 26.0 % of the individuals studied, a rate significantly higher (χ2 = 43.338, p < 0.001) than the prevalence reported in the literature (10.7 %). Multiple VHs (≥2) appeared in 7.2 % of the population studied. VHs prevalence is sex-independent, appearing in 28.6 % of females and 23.5 % of males (χ2 = 0.663, p = 0.416); and age-dependent: the mean age of affected individuals (65.8 years) was significantly higher (p < 0.001) than unaffected individuals (56.2 years). VH size was also age-dependent (p = 0.023). No vertebra was significantly more prone to be affected by a hemangioma. T11 and T12 show the highest prevalence of VHs (3.57 % of vertebrae affected). VHs were found in similar percentages in the anterior and posterior parts of the vertebral body (52.8 vs. 47.2 %, respectively); and at its center and periphery (50.1 and 49.9 %, respectively). VHs usually appeared at mid-height of the vertebral body or slightly higher. Conclusions: The reported prevalence of VHs is dependent on the demographic structure of the population studied, the size of the VHs and the method used to identify them. Overall, the phenomenon is more frequent than usually reported. VHs may appear at all vertebral levels and in all areas of the vertebral body.
AB - Purpose: Vertebral hemangiomas (VHs) are the most common form of benign tumors in the spine. The aim of this research was to study the prevalence of VHs in the human population, their distribution along the spine and their location in the vertebral body. Methods: The presence of VHs was assessed in full spine CT scans of 196 adults. Demographic data were gathered from medical records. Results: VHs were present in 26.0 % of the individuals studied, a rate significantly higher (χ2 = 43.338, p < 0.001) than the prevalence reported in the literature (10.7 %). Multiple VHs (≥2) appeared in 7.2 % of the population studied. VHs prevalence is sex-independent, appearing in 28.6 % of females and 23.5 % of males (χ2 = 0.663, p = 0.416); and age-dependent: the mean age of affected individuals (65.8 years) was significantly higher (p < 0.001) than unaffected individuals (56.2 years). VH size was also age-dependent (p = 0.023). No vertebra was significantly more prone to be affected by a hemangioma. T11 and T12 show the highest prevalence of VHs (3.57 % of vertebrae affected). VHs were found in similar percentages in the anterior and posterior parts of the vertebral body (52.8 vs. 47.2 %, respectively); and at its center and periphery (50.1 and 49.9 %, respectively). VHs usually appeared at mid-height of the vertebral body or slightly higher. Conclusions: The reported prevalence of VHs is dependent on the demographic structure of the population studied, the size of the VHs and the method used to identify them. Overall, the phenomenon is more frequent than usually reported. VHs may appear at all vertebral levels and in all areas of the vertebral body.
KW - Benign tumor
KW - Computed tomography
KW - Spine
KW - Vascular malformation
KW - Vertebral body
UR - http://www.scopus.com/inward/record.url?scp=84957845932&partnerID=8YFLogxK
U2 - 10.1007/s00586-015-4022-y
DO - 10.1007/s00586-015-4022-y
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AN - SCOPUS:84957845932
SN - 0940-6719
VL - 24
SP - 2189
EP - 2195
JO - European Spine Journal
JF - European Spine Journal
IS - 10
ER -