Verapamil-Digoxin Interaction

Herman O. Klein, Robert Lang, Elio Di Segni, Eliezer Kaplinsky

Research output: Contribution to journalLetterpeer-review

62 Scopus citations

Abstract

To the Editor: Dr. Doering wrote in the August 23, 1979, issue that no drug except quinidine influenced the serum levels of digoxin. In Table 1 in his article, specific reference was made to verapamil. Since our experience seems to be different, we think it is important to bring our results to the attention of your readers. In the past five years, we have been treating chronic atrial fibrillation with verapamil to decrease atrioventricular conduction and slow the ventricular rate.* In the course of treating 41 patients, we found that serum digoxin levels increased from 0.96±0.08 to 1.63±0.12 ng per.

Original languageEnglish
Pages (from-to)160
Number of pages1
JournalNew England Journal of Medicine
Volume303
Issue number3
DOIs
StatePublished - 17 Jul 1980
Externally publishedYes

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