Ventricular myosin of the shrew Crocidura russula, correlation with contractile properties

G. Kessler-Icekson*, H. Schlesinger, J. J. Leger, J. Leger, Y. Braverman, O. Binah

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The present study demonstrates that in the shrew ventricular muscle the speed of tension development and relaxation, as well as twitch duration, are much shorter than in the guinea-pig. It also shows that ventricular myosin of the shrrw has a high Ca2+-activated ATPase activity and that it is composed of α-type heavy chains. Namely, the native molecule is a V1 variety of myosin. These findings advance our knowledge on an as yet uncharacterized mammalian heart and further demonstrate the correlation between mechanical properties and myosin type in heart muscle.

Original languageEnglish
Pages (from-to)1069-1073
Number of pages5
JournalJournal of Molecular and Cellular Cardiology
Issue number11
StatePublished - Dec 1988
Externally publishedYes


  • Guinea-pig
  • Isometric twitch characteristics
  • Myosin ATPase
  • Myosin heavy chains
  • Shrew


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