Vasopressin in cardiac arrest and vasodilatory shock: A forgotten drug for new indications

Ron Ben-Abraham, Eran Hadad, Avi A. Weinbroum, Ori Efrati, Gideon Paret*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Vasopressin is a potent endogenous vasoconstrictor that increases blood pressure and systemic vascular resistance. The administration of exogenous vasopressin during closed and open cardiopulmonary resuscitation in humans was shown to be more effective than optimal doses of epinephrine in several clinical studies. We summarize here the recent experimental and clinical date on the use of vasopressin in cardiopulmonary resuscitation and septic shock. As the use of vasopressin in human resuscitation is now in its early stages, it is expected that accumulated future experience will shed more light regarding the risk-benefit aspects of its use.

Original languageEnglish
Pages (from-to)272-276
Number of pages5
JournalIsrael Medical Association Journal
Volume5
Issue number4
StatePublished - 1 Apr 2003

Keywords

  • Cardiopulmonary resuscitation
  • Epinephrine
  • Vasopressin

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