Varicocele: Effect on sperm functions

R. Hauser*, G. Paz, A. Botchan, L. Yogev, H. Yavetz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


Despite the numerous studies published over the past decade, the role of varicocele in male infertility is still controversial. Although more frequent in infertile men, its influence on sperm production or function has not, as yet, been determined. Moreover, the exact mechanism of varicocele action is not clear. We have surveyed the literature, the correlation of varicocele to sperm parameters and to sperm function tests, such as binding capacity, hypo-osmotic swelling test, presence of reactive oxygen species, and in particular, the correlation to fertility potential. Almost every subject examined had contradictory results. Larger control studies may possibly elucidate and clarify the cases in which varicocele is associated to sperm function, and where treatment may improve fertility.

Original languageEnglish
Pages (from-to)482-485
Number of pages4
JournalHuman Reproduction Update
Issue number5
StatePublished - 2001


  • Acrosome reaction
  • Binding tests
  • Hypo osmotic swelling test
  • Reactive oxygen species
  • Sperm function


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