TY - JOUR
T1 - Vancomycin and ceftazidime bioactivities persist for at least 2 weeks in the lumen in ports
T2 - Simplifying treatment of port-associated bloodstream infections by using the antibiotic lock technique
AU - Haimi-Cohen, Y.
AU - Husain, N.
AU - Meenan, J.
AU - Karayalcin, G.
AU - Lehrer, M.
AU - Rubin, L. G.
PY - 2001
Y1 - 2001
N2 - The residual antibiotic concentration of vancomycin (2 mg/ml)- or ceftazidime (2 mg/ml)-heparin solutions instilled in ports in pediatric hematology-oncology patients 1 to 34 days earlier was measured. Antibiotic concentrations of ≥100 μg of either antibiotic per ml persisted for at least 21 days. For treatment of lumenal port infections, antibiotic-heparin dwell times of ≥2 weeks may be appropriate.
AB - The residual antibiotic concentration of vancomycin (2 mg/ml)- or ceftazidime (2 mg/ml)-heparin solutions instilled in ports in pediatric hematology-oncology patients 1 to 34 days earlier was measured. Antibiotic concentrations of ≥100 μg of either antibiotic per ml persisted for at least 21 days. For treatment of lumenal port infections, antibiotic-heparin dwell times of ≥2 weeks may be appropriate.
UR - http://www.scopus.com/inward/record.url?scp=0035034501&partnerID=8YFLogxK
U2 - 10.1128/AAC.45.5.1565-1567.2001
DO - 10.1128/AAC.45.5.1565-1567.2001
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C2 - 11302830
AN - SCOPUS:0035034501
VL - 45
SP - 1565
EP - 1567
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 5
ER -
