TY - JOUR
T1 - Validity and reliability of the Hebrew version of the Brief Questionnaire of Olfactory Disorders (Brief-QOD) and the Self-Reported Mini Olfactory Questionnaire (Self-MOQ)
AU - Hefetz, Tal
AU - Kassem, Firas
AU - Biadsee, Ameen
AU - Hummel, Thomas
AU - Blau, Ilan
AU - Gershnabel-Milk, Dafna
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Objective: To translate and validate Hebrew versions of two patient-reported outcome measure questionnaires: the Self-Reported Mini Olfactory Questionnaire (Self-MOQ) and the Brief Questionnaire of Olfactory Disorders (Brief-QOD). Methods: A forward-backward translation process was conducted for both questionnaires. All participants rated their sense of smell using a general Visual Analog Scale (VAS) ranging from 0 (no dysfunction) to 10 (severe dysfunction). The patient group completed the questionnaires and the SNOT-22 questionnaire once. A control group of healthy participants completed the questionnaires twice to evaluate test-retest reliability. Subsets of both groups took the Sniffin’ Sticks test. Results: The translation process resulted in Hebrew versions deemed clear and culturally appropriate. A total of 91 individuals were enrolled in the control group and 62 in the patient group. The Hebrew versions of the Self-MOQ and Brief-QOD demonstrated high internal consistency (Cronbach’s α of 0.79–0.94 in the full sample) and overall test-retest reliability. The patient group had higher scores than the control group across all measures (p < 0.001). Logistic regression indicated that the Self-MOQ was the strongest predictor of group membership, while the Brief-QOD QOL and Visual Analog Scale components also significantly contributed. Receiver operating characteristic curve analysis identified an optimal Self-MOQ cutoff score of ≥ 2 for distinguishing patients from controls, with excellent accuracy (AUC = 0.97). Conclusions: The Hebrew Self-MOQ and Brief-QOD are reliable and valid tools for assessing olfactory dysfunction in the Hebrew-speaking population. Future research should evaluate questionnaire results after clinical interventions.
AB - Objective: To translate and validate Hebrew versions of two patient-reported outcome measure questionnaires: the Self-Reported Mini Olfactory Questionnaire (Self-MOQ) and the Brief Questionnaire of Olfactory Disorders (Brief-QOD). Methods: A forward-backward translation process was conducted for both questionnaires. All participants rated their sense of smell using a general Visual Analog Scale (VAS) ranging from 0 (no dysfunction) to 10 (severe dysfunction). The patient group completed the questionnaires and the SNOT-22 questionnaire once. A control group of healthy participants completed the questionnaires twice to evaluate test-retest reliability. Subsets of both groups took the Sniffin’ Sticks test. Results: The translation process resulted in Hebrew versions deemed clear and culturally appropriate. A total of 91 individuals were enrolled in the control group and 62 in the patient group. The Hebrew versions of the Self-MOQ and Brief-QOD demonstrated high internal consistency (Cronbach’s α of 0.79–0.94 in the full sample) and overall test-retest reliability. The patient group had higher scores than the control group across all measures (p < 0.001). Logistic regression indicated that the Self-MOQ was the strongest predictor of group membership, while the Brief-QOD QOL and Visual Analog Scale components also significantly contributed. Receiver operating characteristic curve analysis identified an optimal Self-MOQ cutoff score of ≥ 2 for distinguishing patients from controls, with excellent accuracy (AUC = 0.97). Conclusions: The Hebrew Self-MOQ and Brief-QOD are reliable and valid tools for assessing olfactory dysfunction in the Hebrew-speaking population. Future research should evaluate questionnaire results after clinical interventions.
KW - Brief-QOD
KW - Hebrew translation
KW - Olfactory dysfunction
KW - Patient reported outcome measures
KW - Psychometric validation
KW - Self-MOQ
UR - https://www.scopus.com/pages/publications/105022814473
U2 - 10.1186/s41687-025-00961-7
DO - 10.1186/s41687-025-00961-7
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C2 - 41288871
AN - SCOPUS:105022814473
SN - 2509-8020
VL - 9
JO - Journal of Patient-Reported Outcomes
JF - Journal of Patient-Reported Outcomes
IS - 1
M1 - 135
ER -