Vaccines and autoimmune diseases of the adult.

Hedi Orbach, Nancy Agmon-Levin, Gisele Zandman-Goddard

Research output: Contribution to journalReview articlepeer-review

Abstract

Infectious agents contribute to the environmental factors involved in the development of autoimmune diseases possibly through molecular mimicry mechanisms. Hence, it is feasible that vaccinations may also contribute to the mosaic of autoimmunity. Evidence for the association of vaccinations and the development of these diseases is presented in this review. Infrequently reported post-vaccination autoimmune diseases include systemic lupus erythematosus, rheumatoid arthritis, inflammatory myopathies, multiple sclerosis, Guillain-Barré syndrome, and vasculitis. In addition, we will discuss macrophagic myofasciitis, aluminum containing vaccines, and the recent evidence for autoimmunity following the use of human papillomavirus vaccine.

Original languageEnglish
Pages (from-to)90-97
Number of pages8
JournalDiscovery medicine
Volume9
Issue number45
StatePublished - Feb 2010
Externally publishedYes

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