TY - JOUR
T1 - Vaccine preventable diseases in returned international travelers
T2 - Results from the GeoSentinel Surveillance Network
AU - Boggild, Andrea K.
AU - Castelli, Francesco
AU - Gautret, Philippe
AU - Torresi, Joseph
AU - von Sonnenburg, Frank
AU - Barnett, Elizabeth D.
AU - Greenaway, Christina A.
AU - Lim, Poh Lian
AU - Schwartz, Eli
AU - Wilder-Smith, Annelies
AU - Wilson, Mary E.
N1 - Funding Information:
Financial support : GeoSentinel: the Global Surveillance Network of the International Society of Travel Medicine is supported by Cooperative Agreement U50/CCU412347 from the Centers for Disease Control and Prevention.
PY - 2010/10/28
Y1 - 2010/10/28
N2 - Vaccine preventable diseases (VPDs) threaten international travelers, but little is known about their epidemiology in this group. We analyzed records of 37,542 ill returned travelers entered into the GeoSentinel Surveillance Network database. Among 580 (1.5%) with VPDs, common diagnoses included enteric fever (n=276), acute viral hepatitis (n=148), and influenza (n=70). Factors associated with S. typhi included VFR travel (p<0.016) to South Central Asia (p<0.001). Business travel was associated with influenza (p<0.001), and longer travel with hepatitis A virus (p=0.02). 29% of those with VPDs had pre-travel consultations. At least 55% of those with VPDs were managed as inpatients, compared to 9.5% of those with non-VPDs. Three deaths occurred; one each due to pneumococcal meningitis, S. typhi, and rabies. VPDs are significant contributors to morbidity and potential mortality in travelers. High rates of hospitalization make them an attractive target for pre-travel intervention.
AB - Vaccine preventable diseases (VPDs) threaten international travelers, but little is known about their epidemiology in this group. We analyzed records of 37,542 ill returned travelers entered into the GeoSentinel Surveillance Network database. Among 580 (1.5%) with VPDs, common diagnoses included enteric fever (n=276), acute viral hepatitis (n=148), and influenza (n=70). Factors associated with S. typhi included VFR travel (p<0.016) to South Central Asia (p<0.001). Business travel was associated with influenza (p<0.001), and longer travel with hepatitis A virus (p=0.02). 29% of those with VPDs had pre-travel consultations. At least 55% of those with VPDs were managed as inpatients, compared to 9.5% of those with non-VPDs. Three deaths occurred; one each due to pneumococcal meningitis, S. typhi, and rabies. VPDs are significant contributors to morbidity and potential mortality in travelers. High rates of hospitalization make them an attractive target for pre-travel intervention.
KW - Immunization
KW - Surveillance
KW - Travel medicine
UR - http://www.scopus.com/inward/record.url?scp=77958189008&partnerID=8YFLogxK
U2 - 10.1016/j.vaccine.2010.09.009
DO - 10.1016/j.vaccine.2010.09.009
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C2 - 20851081
AN - SCOPUS:77958189008
VL - 28
SP - 7389
EP - 7395
JO - Vaccine
JF - Vaccine
SN - 0264-410X
IS - 46
ER -
