TY - JOUR
T1 - Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine
AU - Bizjak, Mojca
AU - Bruck, Or
AU - Kanduc, Darja
AU - Praprotnik, Sonja
AU - Shoenfeld, Yehuda
N1 - Publisher Copyright:
© 2016.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present.
AB - A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present.
KW - ASIA syndrome
KW - Antiphospholipid antibodies
KW - Human papillomavirus
KW - Immune thrombocytopenic purpura
KW - Molecular mimicry
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=84973863276&partnerID=8YFLogxK
U2 - 10.1053/j.seminhematol.2016.04.014
DO - 10.1053/j.seminhematol.2016.04.014
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AN - SCOPUS:84973863276
SN - 0037-1963
VL - 53
SP - S48-S50
JO - Seminars in Hematology
JF - Seminars in Hematology
M1 - 50869
ER -
