TY - JOUR
T1 - Uterine rupture during pregnancy
T2 - The URIDA (uterine rupture international data acquisition) study
AU - Tinelli, Andrea
AU - Kosmas, Ioannis P.
AU - Carugno, Jose "Tony"
AU - Carp, Howard
AU - Malvasi, Antonio
AU - Cohen, Shlomo B.
AU - Laganà, Antonio Simone
AU - Angelini, Marta
AU - Casadio, Paolo
AU - Chayo, Jenifer
AU - Cicinelli, Ettore
AU - Gerli, Sandro
AU - Palacios Jaraquemada, Josè
AU - Magnarelli, Giulia
AU - Medvediev, Mykhailo V.
AU - Metello, Josè
AU - Nappi, Luigi
AU - Okohue, Jude
AU - Sparic, Radmila
AU - Stefanović, Radomir
AU - Tzabari, Avinoam
AU - Vimercati, Antonella
N1 - Publisher Copyright:
© 2021 International Federation of Gynecology and Obstetrics
PY - 2022/4
Y1 - 2022/4
N2 - Objective: To describe the characteristics and peripartum outcomes of patients diagnosed with uterine rupture (UR) by an observational cohort retrospective study on 270 patients. Methods: Demographic information, surgical history, symptoms, and postoperative outcome of women and neonates after UR were collected in a large database. The statistical analysis searched for correlation between UR, previous uterine interventions, fibroids, and the successive perinatal outcomes in women with previous UR. Results: Uterine rupture was significantly associated with previous uterine surgery, occurring, on average, at 36 weeks of pregnancy in women also without previous uterine surgery. UR did not rise exponentially with an increasing number of uterine operations. Fibroids were related to UR. The earliest UR occurred at 159 days after hysteroscopic myomectomy, followed by laparoscopic myomectomy (251 days) and laparotomic myomectomy (253 days). Fertility preservation was feasible in several women. Gestational age and birth weight seemed not to be affected in the subsequent pregnancy. Conclusion: Data analysis showed that previous laparoscopic and abdominal myomectomies were associated with UR in pregnancy, and hysteroscopic myomectomy was associated at earlier gestational ages. UR did not increase exponentially with an increasing number of previous scars. UR should not be considered a contraindication to future pregnancies.
AB - Objective: To describe the characteristics and peripartum outcomes of patients diagnosed with uterine rupture (UR) by an observational cohort retrospective study on 270 patients. Methods: Demographic information, surgical history, symptoms, and postoperative outcome of women and neonates after UR were collected in a large database. The statistical analysis searched for correlation between UR, previous uterine interventions, fibroids, and the successive perinatal outcomes in women with previous UR. Results: Uterine rupture was significantly associated with previous uterine surgery, occurring, on average, at 36 weeks of pregnancy in women also without previous uterine surgery. UR did not rise exponentially with an increasing number of uterine operations. Fibroids were related to UR. The earliest UR occurred at 159 days after hysteroscopic myomectomy, followed by laparoscopic myomectomy (251 days) and laparotomic myomectomy (253 days). Fertility preservation was feasible in several women. Gestational age and birth weight seemed not to be affected in the subsequent pregnancy. Conclusion: Data analysis showed that previous laparoscopic and abdominal myomectomies were associated with UR in pregnancy, and hysteroscopic myomectomy was associated at earlier gestational ages. UR did not increase exponentially with an increasing number of previous scars. UR should not be considered a contraindication to future pregnancies.
KW - cesarean sections
KW - labor management
KW - myomectomy
KW - pregnancy
KW - related complications
KW - uterine rupture
UR - http://www.scopus.com/inward/record.url?scp=85111242724&partnerID=8YFLogxK
U2 - 10.1002/ijgo.13810
DO - 10.1002/ijgo.13810
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C2 - 34197642
AN - SCOPUS:85111242724
SN - 0020-7292
VL - 157
SP - 76
EP - 84
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 1
ER -