Use of human amniotic membrane in otolaryngologic practice

Yuval Zohar, Yoav P. Talmi, Yehuda Finkelstein, Yitschak Shvili, Rima Sadov, Nelu Laurian

Research output: Contribution to journalArticlepeer-review


Human amnion is a readily available allograft with low antigenicity, high antimicrobial potential, and the ability to foster epithelial- ization. We have used human amniotic membrane in our department for replacing nasal mucosa in Rendu-Osler-Weber disease, as tympanic membrane grafts, and for covering head and neck sites after flap necrosis. Our experience shows moderate success for management of severe epistaxis and excellent results in covering surfaces after flap necrosis. Use of amnion in eardrum perforations was unsuccessful and was discontinued. Properties of human amniotic membrane are listed and its application in the otolaryngologic practice is reviewed.

Original languageEnglish
Pages (from-to)978-980
Number of pages3
Issue number8
StatePublished - Aug 1987
Externally publishedYes


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