TY - JOUR
T1 - Use of handheld reflectance confocal microscopy for in vivo diagnosis of solitary facial papules
T2 - A case series
AU - Fraga-Braghiroli, N. A.
AU - Stephens, A.
AU - Grossman, D.
AU - Rabinovitz, H.
AU - Castro, R. P.R.
AU - Scope, A.
PY - 2014
Y1 - 2014
N2 - Background Reflectance Confocal Microscopy (RCM) can be useful for evaluation of solitary pink papules that are suspicious for skin cancer. RCM has been challenging to apply to curvy facial areas because of the need for attaining full contact between the skin and RCM probe. A smaller diameter handheld RCM probe has been recently introduced to clinical practice. Objective To describe the utility of RCM handheld probe as a bedside adjunct for clinical diagnosis of solitary facial papules. Methods This is a retrospective descriptive case series of six patients presented with a diagnostically equivocal solitary facial papule. All lesions reported were evaluated and imaged clinically, dermoscopically and with handheld RCM, followed by biopsy for histopathological analysis. Results The series included biopsy-proven basal cell carcinomas (BCCs) (n = 2), squamous cell carcinoma (n = 1), sebaceous hyperplasia (n = 1), desmoplastic trichoepithelioma (n = 1) and compound nevus (n = 1). Handheld RCM was easy to apply to the curved facial surfaces and allowed for reaching a correct bedside diagnosis. Conclusion For clinically and dermoscopically equivocal small papules on curved facial surfaces, handheld RCM may be particularly helpful in differentiating benign lesions from skin cancer.
AB - Background Reflectance Confocal Microscopy (RCM) can be useful for evaluation of solitary pink papules that are suspicious for skin cancer. RCM has been challenging to apply to curvy facial areas because of the need for attaining full contact between the skin and RCM probe. A smaller diameter handheld RCM probe has been recently introduced to clinical practice. Objective To describe the utility of RCM handheld probe as a bedside adjunct for clinical diagnosis of solitary facial papules. Methods This is a retrospective descriptive case series of six patients presented with a diagnostically equivocal solitary facial papule. All lesions reported were evaluated and imaged clinically, dermoscopically and with handheld RCM, followed by biopsy for histopathological analysis. Results The series included biopsy-proven basal cell carcinomas (BCCs) (n = 2), squamous cell carcinoma (n = 1), sebaceous hyperplasia (n = 1), desmoplastic trichoepithelioma (n = 1) and compound nevus (n = 1). Handheld RCM was easy to apply to the curved facial surfaces and allowed for reaching a correct bedside diagnosis. Conclusion For clinically and dermoscopically equivocal small papules on curved facial surfaces, handheld RCM may be particularly helpful in differentiating benign lesions from skin cancer.
UR - http://www.scopus.com/inward/record.url?scp=84905051460&partnerID=8YFLogxK
U2 - 10.1111/jdv.12218
DO - 10.1111/jdv.12218
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C2 - 23889040
AN - SCOPUS:84905051460
SN - 0926-9959
VL - 28
SP - 933
EP - 942
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
IS - 7
ER -