Use of Endometrial Scratching in IVF/IUI - A Worldwide Opinion and Clinical Practice Survey

Gon Shoham*, Heli Alexandroni, Milton Leong, Adrian Shulman, Ariel Weissman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Following recent publications regarding the use of the controversial procedure, endometrial scratching (ES), we wish to gain insights into in vitro fertilization (IVF) clinicians' knowledge and practice, including an updated literature review, current versus past utilization, patient selection, timing and frequency. Methods: Internet-based self-report multiple-choice/multiple-answer survey of IVF clinics. Results: Of the 143 IVF units completing the survey, 119 have used ES in IVF/intrauterine insemination (IUI). Of the respondents with ES experience, 94% recommended ES to patients with repeated implantation failure, 32.3% to patients with a thin endometrium, and 3.5% to general IVF/IUI patients. The majority of respondents performed ES only once prior to an IVF cycle. Of current or past ES users, 73% stopped or reduced ES frequency after reading recent ES-related publications. This was despite the finding that 57.2% believed that ES increased implantation and live-birth likelihood in selected IVF/IUI patients. Conclusions: Despite previous widespread utilization of ES, the lack of consensus regarding patient selection, timing, and benefits of the procedure, has prompted many IVF clinicians who used the procedure in the past to abandon the intervention. According to our study, ES is practiced most commonly for patients with repeated implantation failure and performed once during the luteal phase. Further research is needed to obtain definitive practice guidelines based on ES successes and failures-specifically a prospective randomized controlled study according to the methodology used by Barash et al., original publication.

Original languageEnglish
Article number108
JournalClinical and Experimental Obstetrics and Gynecology
Issue number5
StatePublished - May 2022


  • IVF
  • endometrial scratching
  • infertility
  • pregnancy outcomes
  • survey


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