Upper respiratory tract manifestations in yellow nail syndrome

Yellow Nail Syndrome (YNS) is characterized by a triad of ankle edema, pleural effusion and yellow nails. A close association was also found between YNS and rhinitis and sinusitis ranging from 25% to 83%. Although usually other symptoms precede rhinosinusitis, we describe three cases in which the onset of the upper respiratory tract manifestations predated nail changes and other characteristics of YNS. Our aim is to emphasize the importance of upper respiratory tract diseases in this uncommon syndrome.