Unusual neurological manifestations of primary human immunodeficiency virus infection

Sharon Hassin-Baer*, Israel Steiner, Anat Achiron, Menachem Sadeh, Ami Vonsover, David Hassin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The nervous system may be involved during primary human immunodeficiency virus (HIV) infection. Recognized clinical syndromes include meningitis, meningo-encephalitis, myelopathy, polyneuropathy and rhabdomyolysis. We report three patients with unusual neurological presentations of primary HIV infection: intracranial hypertension, severe encephalopathy characterized by personality changes and regressive behavior, and iumbosacral radiculoneuropathy. In all, the neurological disorder had a benign course and resolved within a few months. Awareness of the large spectrum of neurological manifestations of primary HIV infection can enable early diagnosis and treatment.

Original languageEnglish
Pages (from-to)369-373
Number of pages5
JournalEuropean Journal of Neurology
Issue number4
StatePublished - 1998
Externally publishedYes


  • Benign intracranial hypertension
  • Encephalitis
  • HIV
  • Lumbosacral radiculopathy
  • Neurological complications
  • Primary infection
  • Seroconversion


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