Unsuccessful methotrexate treatment of a tubal pregnancy with a live embryo

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Two cases with unsuccessful local and systemic methotrexate (MTX) therapy of tubal pregnancy with fetal heart rate activity are reported. The three modes of therapy, the first with local potassium chloride solution injection, the second with local MTX injection, and the third with systemic MTX injection, failed in the resolution of viable ectopic pregnancy. Therapy of MTX in cases of tubal pregnancy with demonstrable fetal heart rate beats, should be reconsidered.

Original languageEnglish
Pages (from-to)154-157
Number of pages4
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Issue number2-3
StatePublished - 23 Sep 1992


  • Fetal heart rate
  • Methotrexate
  • Tubal pregnancy


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