Unraveling the detoxification mechanism of 2,4-dichlorophenol by marine-derived mesophotic symbiotic fungi isolated from marine invertebrates

Efstratios Nikolaivits, Andreas Agrafiotis, Aikaterini Termentzi, Kyriaki Machera, Géraldine Le Goff, Pedro Álvarez, Suchana Chavanich, Yehuda Benayahu, Jamal Ouazzani, Nikolas Fokialakis, Evangelos Topakas

Research output: Contribution to journalArticlepeer-review

Abstract

Chlorophenols (CPs) are environmental pollutants that are produced through various anthropogenic activities and introduced in the environment. Living organisms, including humans, are exposed to these toxic xenobiotics and suffer from adverse health effects. More specifically, 2,4-dichlorophenol (2,4-DCP) is released in high amounts in the environment and has been listed as a priority pollutant by the US Environmental Protection Agency. Bioremediation has been proposed as a sustainable alternative to conventional remediation methods for the detoxification of phenolic compounds. In this work, we studied the potential of fungal strains isolated as symbionts of marine invertebrates from the underexplored mesophotic coral ecosystems. Hence, the unspecific metabolic pathways of these fungal strains are being explored in the present study, using the powerful analytical capabilities of a UHPLC-HRMS/MS. The newly identified 2,4-DCP metabolites add significantly to the knowledge of the transformation of such pollutants by fungi, since such reports are scarce.

Original languageEnglish
Article number564
JournalMarine Drugs
Volume17
Issue number10
DOIs
StatePublished - 30 Sep 2019

Keywords

  • 2,4-dichlorophenol
  • Bioremediation
  • HRMS/MS
  • Invertebrate symbionts
  • Marine-derived fungi
  • Mesophotic zone
  • Metabolite analysis

Fingerprint

Dive into the research topics of 'Unraveling the detoxification mechanism of 2,4-dichlorophenol by marine-derived mesophotic symbiotic fungi isolated from marine invertebrates'. Together they form a unique fingerprint.

Cite this