TY - JOUR
T1 - Understanding the molecular mechanism of protein translocation across the mitochondrial inner membrane
T2 - Still a long way to go
AU - Marom, Milit
AU - Azem, Abdussalam
AU - Mokranjac, Dejana
PY - 2011/3
Y1 - 2011/3
N2 - In order to reach the final place of their function, approximately half of the proteins in any eukaryotic cell have to be transported across or into one of the membranes in the cell. In this article, we present an overview of our current knowledge concerning the structural properties of the TIM23 complex and their relationship with the molecular mechanism of protein transport across the mitochondrial inner membrane. This article is part of a Special Issue entitled Protein translocation across or insertion into membranes.
AB - In order to reach the final place of their function, approximately half of the proteins in any eukaryotic cell have to be transported across or into one of the membranes in the cell. In this article, we present an overview of our current knowledge concerning the structural properties of the TIM23 complex and their relationship with the molecular mechanism of protein transport across the mitochondrial inner membrane. This article is part of a Special Issue entitled Protein translocation across or insertion into membranes.
UR - http://www.scopus.com/inward/record.url?scp=79851514913&partnerID=8YFLogxK
U2 - 10.1016/j.bbamem.2010.07.011
DO - 10.1016/j.bbamem.2010.07.011
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AN - SCOPUS:79851514913
SN - 0005-2736
VL - 1808
SP - 990
EP - 1001
JO - Biochimica et Biophysica Acta - Biomembranes
JF - Biochimica et Biophysica Acta - Biomembranes
IS - 3
ER -