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Underreporting of Symptomatic Adverse Events in Phase i Clinical Trials
Zachary W. Veitch
,
Daniel Shepshelovich
, Christina Gallagher
, Lisa Wang
, Albiruni R. Abdul Razak
, Anna Spreafico
, Philippe L. Bedard
, Lillian L. Siu
, Lori Minasian
, Aaron R. Hansen
*
*
Corresponding author for this work
Princess Margaret Hospital
Tel Aviv Sourasky Medical Center
University of Toronto
National Institutes of Health
Research output
:
Contribution to journal
›
Article
›
peer-review
49
Scopus citations
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Keyphrases
Phase I Clinical Trial
100%
Symptomatic Adverse Events
100%
Common Terminology Criteria for Adverse Events (CTCAE)
88%
Patient-reported Outcomes
66%
Mid-cycle
33%
Clinician Rating
22%
Reporting Frequency
22%
Phase I Trial
22%
Nineteen
11%
Patient Characteristics
11%
Reporting Rate
11%
Dyspnea
11%
Leg Edema
11%
Best Response
11%
Prospective Observational Study
11%
Patient Report
11%
Peripheral Neuropathy
11%
Survival Data
11%
Phase I Study
11%
Frequency Ratio
11%
Response Data
11%
Underreported
11%
Princess
11%
Sexual Health
11%
Trial Characteristics
11%
Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events
11%
Survey Completion Rate
11%
Medicine and Dentistry
Adverse Event
100%
Clinical Trial
100%
Clinician
55%
Patient-Reported Outcome
38%
Phase I Trials
11%
Dyspnea
5%
Observational Study
5%
Peripheral Edema
5%
Neuropathy
5%
Sexual Health
5%
Nursing and Health Professions
Adverse Event
100%
Patient-Reported Outcome
38%
Neuropathy
5%
Peripheral Edema
5%
Dyspnea
5%
Agricultural and Biological Sciences
Observational Studies
100%