Uncertainties in diagnosis, treatment and prevention of trichinellosis

Zvi Shimoni, Paul Froom*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

This review summarizes expert opinion and evidence on the diagnosis, treatment and prevention of trichinellosis. Laboratory test results are not sufficiently sensitive for the diagnosis of individual patients when outbreaks are suspected. A likely diagnosis depends on identifying a potential common source of exposure supported by detection of antibodies to Trichinella antigens in a higher than expected proportion of exposed patients. Expert opinion is discordant, but for patients with symptomatic disease, there are theoretical reasons to recommend treatment with albendazole (rather than mebendazole) taken with fatty meals and prednisone. Education of the public is probably not a reliable way to prevent trichinellosis and when feasible should be augmented with mandatory testing of all potentially infected meat.

Original languageEnglish
Pages (from-to)1279-1288
Number of pages10
JournalExpert Review of Anti-Infective Therapy
Volume13
Issue number10
DOIs
StatePublished - 3 Oct 2015

Keywords

  • albendazole
  • complications
  • corticosteroids
  • diagnosis
  • laboratory tests
  • mebendazole
  • prevention
  • symptoms
  • trichinellosis

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