Ultrastructural observation on blast cells of a patient with acute basophilic leukemia

A. M. Cohen, S. Alexandrova, Z. Cycowitz, H. Bessler, M. Djaldetti*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The case history of a 70-year-old man with acute basophilic leukemia is presented. While light microscopic examination of the blast cells in the peripheral blood and in the bone marrow was inconclusive, the ultrastructural analysis of the cells helped to establish the diagnosis. The most prominent findings in the blast cells examined with the electron microscope were the basophilic differentiation, presence of basophilic granules with granular and/or fibrillar structure and cytoplasmic formations resembling Auer bodies. In addition, the cytoplasm contained crystalloid inclusions and filaments. The results indicate that electron microscopic examination of the blast cells in certain cases of acute non-lymphocytic leukemia may be of important diagnostic value.

Original languageEnglish
Pages (from-to)434-436
Number of pages3
JournalCell Vision - Journal of Analytical Morphology
Volume3
Issue number6
StatePublished - 1996
Externally publishedYes

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