Ultrastructural alterations of peripheral blood cells due to Vipera palaestinae snake bite

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Abstract

The ultra-structural alterations of the circulating red blood cells, lymphocytes and platelets of a patient bitten by a Vipera palaestinae snake were observed with transmission and scanning electron microscopes. The red blood cells showed a marked echinocyte transformation. The lymphocytes revealed shortening and "rarefaction" of their microvilli, as well as decrease in the number of cell organelles. The platelets showed shortened cytoplasmic processes, increased glycogen content, reduced number and abnormal mitochondria. The possible role of venom phospholipase A, as an inducer of some of these alterations is discussed.

Original languageEnglish
Pages (from-to)379-384
Number of pages6
JournalToxicon
Volume15
Issue number5
DOIs
StatePublished - 1977
Externally publishedYes

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