TY - JOUR
T1 - Typhoid Hepatitis With Immunoglobulins and Complement Deposits in Bile Canaliculi
AU - Dan, Michael
AU - Bar-Meir, Simon
AU - Jedwab, Medina
AU - Shibolet, Shlomo
PY - 1982/1
Y1 - 1982/1
N2 - Documented typhoid fever in a 26-year-old patient was complicated by acute hepatitis with unusually profound jaundice. Liver biopsy revealed focal cell necrosis, mononuclear cell infiltration, Kupffer cell proliferation, and mild cholestasis. Immunofluorescent studies of the liver biopsy revealed deposits of IgG, IgA, IgM, and C3 in the bile canaliculi, suggesting a role for damage by immune complexes in typhoid hepatitis.
AB - Documented typhoid fever in a 26-year-old patient was complicated by acute hepatitis with unusually profound jaundice. Liver biopsy revealed focal cell necrosis, mononuclear cell infiltration, Kupffer cell proliferation, and mild cholestasis. Immunofluorescent studies of the liver biopsy revealed deposits of IgG, IgA, IgM, and C3 in the bile canaliculi, suggesting a role for damage by immune complexes in typhoid hepatitis.
UR - http://www.scopus.com/inward/record.url?scp=0020059361&partnerID=8YFLogxK
U2 - 10.1001/archinte.1982.00340140150027
DO - 10.1001/archinte.1982.00340140150027
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AN - SCOPUS:0020059361
SN - 0003-9926
VL - 142
SP - 148
EP - 149
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 1
ER -
