Type-specific streptococcal antibodies in pyodermal nephritis

Sonia Bergner-Rabinowitz*, Itzhak Ofek, Michael A. Davies, Kurt Rabinowitz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Type-specific antibodies in 656 samples of sera from 94 patients with glomerulonephritis associated with Group A streptococci provisional M-type 55, which was new to Israel, were studied. The antibodies were assayed by a micro-opsonophago- cytic method, using an in-vitro system of phagocytosis with peritoneal leukocytes from mice. All the sera were tested against provisional type 55. A sample of 270 sera collected from 40 patients was examined also against provisional type 60 and types 12, 25, and 49. Antibodies against provisional types 55 and 60 were found in a significant percentage of patients as compared with controls. In most cases, antibodies were detected two to four months after the initial disease and waned gradually over a period of five to seven months. The practical and potential usefulness of the test for type-specific antibody in nephritic patients is discussed.

Original languageEnglish
Pages (from-to)488-493
Number of pages6
JournalJournal of Infectious Diseases
Issue number5
StatePublished - Nov 1971
Externally publishedYes


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