Type C virus and immunoglobulin A production by murine myeloma MOPC-315: Two independent activities

A. Gazit, A. Yaniv, D. Halperin, S. Ben-Efraim

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The suspected correlation between cessation of type C virus production and halt in immunoglobulin secretion by murine myeloma cells was studied. Employing two variants of the murine myeloma MOPC-315, immunoglobulin A-producing and nonproducing cells, we demonstrated that the two myelomas release similar levels of type C viruses which share common nucleotide sequences and that the viral genomes are equally expressed within the cells. Thus, the suggested relation between these two activities does not apply for MOPC-315 cells and probably for other murine myelomas also.

Original languageEnglish
Pages (from-to)569-573
Number of pages5
JournalInfection and Immunity
Volume25
Issue number2
DOIs
StatePublished - 1979

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