TY - JOUR
T1 - Type 2 diabetes mellitus and cardiovascular diseases
T2 - Evaluation, treatment and prevention strategies
AU - Mosseri, Morris M.
AU - Fisman, Enrique Z.
AU - Tenenbaum, Alexander
PY - 2006/2
Y1 - 2006/2
N2 - Patients with type 2 diabetes mellitus are at high risk for cardiovascular events and heart failure. The major serious complication of this disorder is large vessel atherosclerosis leading to myocardial infarction and stroke. Aggressive target setting for modifiable cardiovascular risk factors such as dyslipidemia, hypertension, and a procoagulant state, and judicious choice of efficacious therapies have been shown to produce significant reductions in cardiovascular events. The effectiveness of percutaneous coronary intervention (PCI) in diabetes is discussed, and the factors that may influence outcomes are explored. A major unresolved question is the potential role of tight glucose control for reducing macrovascular complications in patients with diabetes. With the increased attention being given to cardiovascular risk factor reduction, the opportunity exists to substantially decrease the largest causes of mortality in diabetic patients. This article reviews the current and emerging therapeutic strategies for these purposes from the cardiologists' point of view.
AB - Patients with type 2 diabetes mellitus are at high risk for cardiovascular events and heart failure. The major serious complication of this disorder is large vessel atherosclerosis leading to myocardial infarction and stroke. Aggressive target setting for modifiable cardiovascular risk factors such as dyslipidemia, hypertension, and a procoagulant state, and judicious choice of efficacious therapies have been shown to produce significant reductions in cardiovascular events. The effectiveness of percutaneous coronary intervention (PCI) in diabetes is discussed, and the factors that may influence outcomes are explored. A major unresolved question is the potential role of tight glucose control for reducing macrovascular complications in patients with diabetes. With the increased attention being given to cardiovascular risk factor reduction, the opportunity exists to substantially decrease the largest causes of mortality in diabetic patients. This article reviews the current and emerging therapeutic strategies for these purposes from the cardiologists' point of view.
KW - Coronary artery disease
KW - Diabetes mellitus
KW - Percutaneous coronary intervention
UR - http://www.scopus.com/inward/record.url?scp=33646905073&partnerID=8YFLogxK
M3 - סקירה
AN - SCOPUS:33646905073
VL - 145
SP - 141
EP - 146
JO - Harefuah
JF - Harefuah
SN - 0017-7768
IS - 2
ER -