Two Roads Diverge in the Sick Liver, Monocytes Travel Both

Ehud Zigmond; Chen Varol

doi:10.1016/j.immuni.2020.08.006

Two Roads Diverge in the Sick Liver, Monocytes Travel Both

Ehud Zigmond, Chen Varol^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate

7 Scopus citations

Abstract

Liver macrophages play critical roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). In this issue of Immunity, Tran et al. and Remmerie et al. reveal that Ly6C^hi monocytes in NASH replace dying resident Kupffer cells, while concomitantly are differentiating into distinct lipid associated macrophages.

Original language	English
Pages (from-to)	479-481
Number of pages	3
Journal	Immunity
Volume	53
Issue number	3
DOIs	https://doi.org/10.1016/j.immuni.2020.08.006
State	Published - 15 Sep 2020

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title = "Two Roads Diverge in the Sick Liver, Monocytes Travel Both",

abstract = "Liver macrophages play critical roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). In this issue of Immunity, Tran et al. and Remmerie et al. reveal that Ly6Chi monocytes in NASH replace dying resident Kupffer cells, while concomitantly are differentiating into distinct lipid associated macrophages.",

author = "Ehud Zigmond and Chen Varol",

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year = "2020",

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AB - Liver macrophages play critical roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). In this issue of Immunity, Tran et al. and Remmerie et al. reveal that Ly6Chi monocytes in NASH replace dying resident Kupffer cells, while concomitantly are differentiating into distinct lipid associated macrophages.

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Two Roads Diverge in the Sick Liver, Monocytes Travel Both

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