Two-locus autosomal sex determination: On the evolutionary genetic stability of the even sex ratio

Uri Liberman*, Marcus W. Feldman, Ilan Eshel, Sarah P. Otto

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

In two-locus models of sex determination, there are two kinds of interior (polymorphic) equilibria. One class has the even sex ratio, and the other has equal allele frequencies in the two sexes. Equilibria of the second class may exhibit linkage disequilibrium. The condition for external stability of these second-class equilibria to invasion by a new allele is that the appropriately averaged sex ratio near the equilibrium be moved closer to the even sex ratio than the average among the resident genotypes. However, invasion by a new chromosome depends on the recombination fraction in a way that appears to preclude general results about the evolutionary genetic stability of the even sex ratio in this situation.

Original languageEnglish
Pages (from-to)2013-2017
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume87
Issue number5
DOIs
StatePublished - Mar 1990

Funding

FundersFunder number
National Institute of General Medical SciencesR01GM028016

    Keywords

    • Classes of polymorphisms
    • Linkage
    • Long-term evaluation
    • Population-genetic models

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